You might recall the warning from fifteen years ago from the World Health Organization that smoked, pickled, and undercooked fish contains parasites. This hit home recently when a friend who adores sushi complained of pain in her ribs and made a medical appointment. An increased number of white blood cells indicated an infection. It was only after she told her doctor she consumed raw fish regularly did her doctor suspect an infestation of anisakiasis nematodes (worms) in her stomach lining and intestines. Two drugs (albendazole and mebendazole) are fast-acting and also used by WHO, thanks to donations from GlaxoSmithKline and Johnson & Johnson. If left untreated, the parasites invade other organs including the brain.
Sea mammals such as seals act as the parasites’ hosts, and dissections from marine biologists tell us the problem is worldwide.
I get ideas for villains from current news topics. In my work-in-progress, Bittersweet Alliance, the serial killer serves Poke (raw fish appetizers popular in Hawaii) to kidnapped victims. After ransoms are paid, the victims return home with severe worm infestation in their brains. Surgical procedures to remove (massive numbers of) parasites leave victims’ brains impaired. The serial killer leaves victims brain-dead and is using a popular food where the book is set, the Big Island of Hawaii.